Drusen in age-related macular degeneration
نویسندگان
چکیده
منابع مشابه
Autofluorescence distribution associated with drusen in age-related macular degeneration.
PURPOSE To determine whether drusen in patients with age-related maculopathy and macular degeneration (ARM/AMD) are associated with focal changes in retinal pigment epithelium (RPE) lipofuscin fluorescence. METHOD A new autofluorescence imaging device was used to study lipofuscin distribution associated with individual drusen in 20 patients with ARM/AMD. Paired monochromatic and autofluoresce...
متن کاملFluorescence Lifetimes of Drusen in Age-Related Macular Degeneration.
Purpose The purpose of this study was to characterize fundus autofluorescence lifetimes of retinal drusen in patients with AMD. Methods Patients with AMD and retinal drusen and healthy controls of similar age were examined. A fluorescence lifetime imaging ophthalmoscope was used. Retinal autofluorescence was excited using a 473-nm pulsed laser, and fundus autofluorescence lifetimes of the cen...
متن کاملDynamic soft drusen remodelling in age-related macular degeneration.
AIMS To demonstrate and quantify the dynamic remodelling process of soft drusen resorption and new drusen formation in age-related macular degeneration (AMD) with novel interactive methods. METHODS Twenty patients with large soft drusen bilaterally and without advanced AMD were imaged at baseline and again at a mean interval of 2 years (40 eyes, 80 images). Each of the 40 serial pairs of imag...
متن کاملبررسی اثر چندشکلی ژنتیکی xrcc7 با ریسک ابتلا به بیماریamd age-related macular degeneration))
amd بیماری تحلیل شبکیه است که عامل اصلی کوری در افراد بالای 55 سال در جهان غرب به شمار می-رود. در اثر این بیماری، لیپوپروتئین ها در شبکیه تجمع پیدا کرده و رگ زایی القاء می شود. ثابت شده است که عوامل ژنوتوکسیک محیطی مثل سیگار کشیدن، رژیم غذایی و نور در افراد پیر با زمینه ی ژنتیکی مستعد در بروز بیماری دخیل می باشند. بنابراین ما یک مطالعه ی مـورد- شاهـدی را ترتیب دادیم که شـامل 112 فرد مبتلا به am...
the genetics of age-related macular degeneration
age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...
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ژورنال
عنوان ژورنال: Eye
سال: 1994
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.1994.56